Ovarian cancer is the second most common gynecologic malignancy and the most common cause of gynecologic cancer death in the United States. There are approximately 22,000 new cases and 14,000 cancer-related deaths expected from ovarian cancer each year.
Uterine cancer is the most common gynecologic malignancy in the United States; there were approximately 50,000 new cases and over 8,000 deaths from this disease in 2013.
In the United States, over 12,000 new cases of invasive cervical cancer and approximately 4,000 cervical cancer-related deaths occur each year. Cervical cancer is the third most common cancer diagnosis and cause of death among gynecologic cancers in the United States.
Vulvar cancer is the fourth most common gynecologic cancer and comprises five percent of malignancies of the female genital tract. Within the United States, approximately 4700 cases are diagnosed each year, with nearly 1000 of those women expected to succumb to their disease. Although various histologic subtypes of vulvar cancer exist, the vast majority is comprised of squamous cell carcinoma (SCC).
Vaginal cancer comprises approximately three percent of all malignant neoplasms of the female genital tract. Approximately 2,900 cases are diagnosed annually in the United States, with about 800 deaths.
Gestational Trophoblastic Disease (GTD) is the abnormal growth of cells in the uterus that is usually associated with an abnormal placental or pregnancy tissue. Usually this is diagnosed when a woman suspects or knows she is pregnant. Typically there is bleeding in these pregnancies or an abnormal ultrasound.